This includes an increased risk of multiple bone fractures in the spine. Skipping a dose of Prolia or stopping use of the drug increases the risk of bone fractures. Risk of bone fractures after skipping or stopping treatment They may also recommend that you stop using Prolia and try a different medication for your condition. Your doctor may recommend treatment for your pain, depending on the severity. Fractures can cause joint pain, even when the fracture isn’t in the joint itself. They may want to check you for fractures. If you have any joint pain while using Prolia, talk with your doctor.īut if your pain is severe, it’s important to contact your doctor right away. But after these studies were done, some people have reported severe joint pain while using Prolia. Pain, including joint pain, is a possible side effect of Prolia. You should also contact your doctor or dentist if you experience pain or slow healing following dental surgery.īefore you have any dental procedure, be sure to tell your dentist that you’re using Prolia. If you notice any symptoms of dental or jaw-related side effects while using Prolia, contact your doctor or dentist right away. This can help prevent dental and jaw-related side effects that Prolia might cause. You should practice good oral hygiene while using Prolia, including brushing and flossing your teeth. They may recommend that you see a dentist before starting Prolia. What might helpīefore you begin treatment with Prolia, your doctor should examine your mouth. According to the American Dental Association, the risk of jaw necrosis increases if denosumab, the active drug in Prolia, is used for more than 2 years. This may cause teeth to become loose and need to be removed. One potential complication is jaw necrosis (death of jawbone tissue). Symptoms of dental and jaw-related side effects can include: Dental and jaw-related side effectsĪlthough rare, it’s possible to have dental and jaw-related side effects from using Prolia. Learn more about some of the side effects Prolia may cause.
If you’d like to notify the FDA about a side effect you’ve had with Prolia, visit MedWatch. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. See the Prolia medication guide for more information. Prolia may cause mild side effects other than the ones listed above. And don’t stop using Prolia unless your doctor tells you to. But if you have any symptoms that are ongoing or that bother you, talk with your doctor or pharmacist. In most cases, these side effects should be temporary. Mild side effects in people receiving certain treatments for breast or prostate cancer while also using Prolia to help prevent bone loss include:
Mild side effects in people using Prolia for osteoporosis caused by taking glucocorticoid drugs include: Mild side effects in males* using Prolia for osteoporosis include: sciatica (a shooting pain from the lower back down to one of the legs).upper respiratory tract infections, such as the common cold.Mild side effects in females* using Prolia for osteoporosis after menopause include: What are the mild side effects of Prolia? † To learn more about this side effect, see “Side effects explained” below. For information about the difference between sex and gender, see this article. * In this article, we use the terms “male” and “female” to refer to someone’s sex assigned at birth. More common side effects in people receiving certain treatments for breast or prostate cancer while also using Prolia to help prevent bone loss include: More common side effects in people using Prolia for osteoporosis caused by taking glucocorticoid drugs include: common cold symptoms, like a runny nose or sore throat.More common side effects in males* using Prolia for osteoporosis include: More common side effects in females* using Prolia for osteoporosis after menopause include: These side effects can vary depending on which condition the drug is being used to treat or prevent. These are just a few of the more common side effects reported by people who took Prolia in studies. What are the more common side effects of Prolia?
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